Infection by cytomegalovirus in patients with neonatal cholestasis
نویسندگان
چکیده
منابع مشابه
Infection by cytomegalovirus in patients with neonatal cholestasis.
BACKGROUND Neonatal cholestasis syndrome with an intra or extrahepatic origin has been associated to viral infections. The participation of the cytomegalovirus in the etiopathogenesis of neonatal hepatitis has been already known for some time, but only recently there have been indications that this virus may be one of the possible etiological factors for extrahepatic biliary atresia. AIMS To ...
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Neonatal cholestasis is a prolonged elevation of the serum levels of conjugated bilirubin beyond the first 14 days of life. Commonest etiologies include extrahepatic conditions like biliary atresia, intrahepatic like congenital malformations, infections and inborn errors of metabolism. TORCH infections constitute 22% cases of neonatal hepatitis, of which Cytomegalovirus is the commonest agent. ...
متن کاملCytomegalovirus DNA detection on Guthrie cards in patients with neonatal cholestasis.
AIM To time the onset of cytomegalovirus (CMV) infection in patients (n = 39) with CMV associated neonatal cholestasis by analysing CMV DNA on Guthrie cards sampled at 3 days of age. METHODS CMV infection was diagnosed by serology/urine isolation or by CMV DNA detection (polymerase chain reaction) in liver biopsy specimens. In order to time the infection dry blood filter paper discs were punc...
متن کاملGanciclovir treatment in infants with cytomegalovirus infection and cholestasis.
BACKGROUND The authors have previously described an association between cytomegalovirus (CMV) infection and intrahepatic and extrahepatic forms of neonatal cholestasis. Pediatric use of the antiviral drug ganciclovir to treat patients with CMV infection has increased. In this study, infants with CMV infection and cholestasis were treated with ganciclovir. METHODS Six infants with cholestasis ...
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ژورنال
عنوان ژورنال: Arquivos de Gastroenterologia
سال: 2002
ISSN: 0004-2803
DOI: 10.1590/s0004-28032002000200012