منابع مشابه
Substrate-specific inactivation of staphylococcal penicillinase.
1. The rate of hydrolysis of methicillin, cloxacillin and quinacillin by staphylococcal extracellular penicillinase decreases progressively with time. 2. The inactivation is prevented but not reversed by benzylpenicillin. 3. The rate of inactivation produced by quinacillin is minimal when the rate of hydrolysis is at a maximum. 4. Under certain conditions, partially inactivated enzyme can be re...
متن کاملInteraction of Staphylococcal Penicillinase and 6-[D(-
Citri and Zyk (3) recently showed that the penicillinase of Bacillus cereus, on interaction with substrates, may yield conformational changes at the active site of the enzyme. Earlier studies by a number of investigators (1, 2, 4, 6, 8, 11) showed that penicillin analogues resistant to staphylococcal penicillinase, such as methicillin, may cause inactivation ofthe enzyme. In contrast, Richmond ...
متن کاملIn Vivo Studies on Staphylococcal Penicillinase.
Eyckmans, Luc (Baylor University Medical Center, Dallas, Tex.), and Ralph Tompsett. In vivo studies on staphylococcal penicillinase. J. Bacteriol. 90:589-593. 1965.-The amounts of staphylococcal penicillinase present in tissue of mice with well-established infections due to penicillin-resistant staphylococci were determined. The data indicate that, in the presence of such infection, penicillina...
متن کاملNew Assay for Penicillinase and Some Results on Penicillinase Induction.
Imsande, John (Western Reserve University, Cleveland, Ohio). New assay for penicillinase and some results on penicillinase induction. J. Bacteriol. 89:1322-1327. 1965.-A rapid, sensitive, and reliable assay of penicillinase activity is described. Studies conducted on the induction of penicillinase, with use of the new assay, show that actinomycin D inhibits growth and the induced synthesis of p...
متن کاملStaphylococcal penicillinase. I. Inhibition and stimulation of activity.
Saz, Arthur K. (National Institute of Allergy and Infectious Diseases, Bethesda, Md.), Dolores L. Lowery, and Leah J. Jackson. Staphylococcal penicillinase. I. Inhibition and stimulation of activity. J. Bacteriol. 82:298-304. 1961.-The penicillinase extracted from a penicillin-resistant strain of Staphylococcus aureus was shown to be inhibited up to 70% by various dipeptides and particularly by...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1957
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.73.1.28-34.1957