Induction of Penicillinase with Inorganic Phosphate

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Induction of penicillinase with inorganic phosphate.

Phosphate stimulates penicillinase formation in Bacillus cereus 569. The rate of penicillinase synthesis in the presence of 0.3 m phosphate, pH 7.0, is approximately 10-fold greater than that for uninduced cells, while the rate of synthesis in the presence of 0.3 m phosphate and 1 unit/ml of penicillin is approximately fourfold greater than in the presence of penicillin alone. When phosphate-in...

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New Assay for Penicillinase and Some Results on Penicillinase Induction.

Imsande, John (Western Reserve University, Cleveland, Ohio). New assay for penicillinase and some results on penicillinase induction. J. Bacteriol. 89:1322-1327. 1965.-A rapid, sensitive, and reliable assay of penicillinase activity is described. Studies conducted on the induction of penicillinase, with use of the new assay, show that actinomycin D inhibits growth and the induced synthesis of p...

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Inorganic Phosphate Homeostasis

to transport Pi according to the dietary Pi: TRPt was always higher, for a given [Pt]P1, in the animals fed low than in those fed higher Pi diets. This diet-induced modification also occurred in the absence of thyroparathyroid glands, in the presence of the same calcemia and urinary pH, and during marked extracellular volume expansion. A time-course study in rats TPTX both before and during the...

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Induction of penicillinase by staphylococci in vitro and in vivo.

Eyckmans, Luc (Cornell University Medical College, New York, N.Y.), and Edward W. Hook. Induction of penicillinase by staphylococci in vitro and in vivo. J. Bacteriol. 91:997-1003. 1966.-Staphylococci in mice with peritoneal infection showed no significant increase in penicillinase activity 6 hr after administration of penicillin G. In contrast, induction of penicillinase was readily demonstrat...

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Micropuncture Study of Inorganic Phosphate Excretion

The mechanism by which the mammalian kidney excretes inorganic phosphate has not been fully elucidated. The only micropuncture data available are those of Walker and Hudson (1), and they deal with the mode of phosphate excretion in two amphibian species. These investigators reported that the inorganic phosphate concentration rises progressively along the proximal and distal nephron of the frog ...

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ژورنال

عنوان ژورنال: Journal of Bacteriology

سال: 1967

ISSN: 0021-9193,1098-5530

DOI: 10.1128/jb.94.5.1672-1678.1967