Increasing disease resistance in host plants through genome editing

Diseases caused by plant pathogens pose significant challenges to crop yield and quality, thus incurring a serious constraint on the global food supply. Genome editing using clustered regularly interspaced short palindromic repeats (CRISPR)-Cas (CRISPR-associated nuclease) system has revolutionized field of biology biotechnology. New technologies derived from CRISPR-Cas enable genetic improvement for disease resistance development tools early detection pathogens. This review discusses canonical advanced genome available understanding host–pathogen interaction developing host resistance. We categorically cite examples use technology in disease-resistant crops. CRISPR-Cas9 have enabled us apply novel strategies confer against several like bacteria, viruses, fungi, nematodes. CRISPR diagnostic methods been developed leveraging system’s precise ability bind cleave nucleic acids. also discussed different CRISPR-diagnostic fast detection.