Increased Risk of Mycobacterium tuberculosis Infection in Household Child Contacts Exposed to Passive Tobacco Smoke

IFNγ Response to Mycobacterium tuberculosis, Risk of Infection and Disease in Household Contacts of Tuberculosis Patients in Colombia

OBJECTIVES Household contacts (HHCs) of pulmonary tuberculosis patients are at high risk of Mycobacterium tuberculosis infection and early disease development. Identification of individuals at risk of tuberculosis disease is a desirable goal for tuberculosis control. Interferon-gamma release assays (IGRAs) using specific M. tuberculosis antigens provide an alternative to tuberculin skin testing...

Incident Mycobacterium tuberculosis infection in household contacts of infectious tuberculosis patients in Brazil

BACKGROUND In household contact investigations of tuberculosis (TB), a second tuberculin skin test (TST) obtained several weeks after a first negative result consistently identifies individuals that undergo TST conversion. It remains unclear whether this delay in M. tuberculosis infection is related to differences in the infectious exposure, TST boosting, partial host resistance, or some other ...

Author’s response to reviews Title: Incident Mycobacterium tuberculosis Infection in Household Contacts of Infectious Tuberculosis patients in Brazil Authors:

Risk of tuberculosis among household contacts in Salvador, Bahia.

UNLABELLED Tuberculosis is one of the most important infectious diseases in the world. Only 68% of the estimated new tuberculosis (TB) cases in Brazil are diagnosed. Our aim was to determine the risk of infection among household contacts. STUDY DESIGN Cohort of tuberculin-negative household contacts followed for 12 months. METHODS Household contacts of randomly selected index acid-fast baci...

Parental risk perceptions of child exposure to tobacco smoke

BACKGROUND Tobacco smoke exposure harms children and adults. Yet, 40% of children worldwide are exposed to tobacco smoke in their homes. Such widespread parental failure to protect children is puzzling, and may be related to risk perceptions. No consensus exists about how to measure parental risk perceptions of tobacco smoke exposure. METHODS The objective of this research was to study Parent...