Increased intestinal permeability in inflammatory bowel diseases assessed by iohexol test
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چکیده
منابع مشابه
Intestinal Permeability Regulation by Tight Junction: Implication on Inflammatory Bowel Diseases
Epithelial tight junctions (TJs) are the key structures regulating paracellular trafficking of macromolecules. The TJ is multi-protein complex that forms a selective permeable seal between adjacent epithelial cells and demarcates the boundary between apical and basolateral membrane domains. Disruption of the intestinal TJ barrier, followed by permeation of luminal noxious molecules, induces a p...
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BACKGROUND The precise site of intestinal permeability changes in patients with coeliac and inflammatory bowel disease is unknown. AIMS To design a non-invasive technique for the localisation of altered gastrointestinal permeability to 51chromium labelled EDTA (51CrEDTA). The method depends on comparing and defining concentration/time profiles in serum of a series of simultaneously ingested i...
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Introduction: Disorders in intestinal permeability have been reported in the pathophysiology of inflammatory bowel diseases (IBD) that may be compensated by complementary therapies through modifying the composition of the intestinal microflora. This study was designed to evaluate the effect of probiotic yogurt on intestinal permeability in patients with IBD. Materials and Methods: In this doubl...
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Recent studies on human inflammatory bowel diseases (IBD) have brought our attention to continued epithelial injury and impaired epithelial regeneration as their key pathophysiological features. In order to develop a novel approach for the treatment of IBD, it is important to understand the ordered process of epithelial repair and the pivotal roles for the epithelial stem cells in this process....
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Macrophages as innate immune cells and fast responders to antigens play a central role in protecting the body from the luminal content at a huge interface. Chronic inflammation in inflammatory bowel diseases massively alters the number and the subset diversity of intestinal macrophages. We here address the diversity within the human intestinal macrophage compartment at the level of similarities...
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ژورنال
عنوان ژورنال: World Journal of Gastroenterology
سال: 2011
ISSN: 1007-9327
DOI: 10.3748/wjg.v17.i17.2211