Increased Concentrations of Cell-Free Plasma DNA after Exhaustive Exercise

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Increased concentrations of cell-free plasma DNA after exhaustive exercise.

Increased Concentrations of Cell-Free Plasma DNA after Exhaustive Exercise, Johanna Atamaniuk, Claudia Vidotto, Harald Tschan, Norbert Bachl, Karl M. Stuhlmeier, and Mathias M. Müller ( Institute of Laboratory Diagnostics, Kaiser Franz Josef Hospital, Vienna, Austria; 2 Institute of Sports Science, Department of Sports and Exercise Physiology, University of Vienna, Vienna, Austria; 3 Ludwig Bol...

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Plasma NT‐proBNP and Cell‐Free DNA Concentrations after Prolonged Strenuous Exercise in Working Farm Dogs

BACKGROUND Plasma N-terminal pro-B-type natriuretic peptide (NT-proBNP) concentration is increased in dogs with myocardial dysfunction, and cell-free DNA (cfDNA) increases in numerous disease states. In humans, both of these biomarkers can be altered after endurance exercise. OBJECTIVE To investigate the effect of prolonged strenuous exercise on circulating NT-proBNP and cfDNA concentrations ...

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DNA immediately after exhaustive exercise and its disap-

pearance within 2 h after the race suggests that cell-free plasma DNA could possibly be an important tool for monitoring and quantification of cellular damage. Experiments are ongoing in our laboratories to determine whether apoptotic or necrotic events are responsible for the observed phenomenon. Although it seems likely that the source of cell-free plasma DNA is the skeletal muscle cell, furt...

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Lymphocyte apoptosis after exhaustive and moderate exercise.

Apoptosis or programmed cell death is a process of fundamental importance for regulation of the immune response. Several reasons suggest that apoptosis is involved in exercise-induced alterations of the immune system such as postexercise lymphocytopenia. Healthy volunteers performed two treadmill exercise tests; the first was performed at 80% maximal oxygen uptake until exhaustion (exhaustive e...

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ژورنال

عنوان ژورنال: Clinical Chemistry

سال: 2004

ISSN: 0009-9147,1530-8561

DOI: 10.1373/clinchem.2004.034553