Increased bovine Tim-3 and its ligand expressions during bovine leukemia virus infection

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Increased bovine Tim-3 and its ligand expressions during bovine leukemia virus infection

The immunoinhibitory receptor T cell immunoglobulin domain and mucin domain-3 (Tim-3) and its ligand, galectin-9 (Gal-9), are involved in the immune evasion mechanisms for several pathogens causing chronic infections. However, there is no report concerning the role of Tim-3 in diseases of domestic animals. In this study, cDNA encoding for bovine Tim-3 and Gal-9 were cloned and sequenced, and th...

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ژورنال

عنوان ژورنال: Veterinary Research

سال: 2012

ISSN: 1297-9716

DOI: 10.1186/1297-9716-43-45