Incorporating Single-Locus Tests into Haplotype Cladistic Analysis in Case-Control Studies
نویسندگان
چکیده
منابع مشابه
Incorporating Single-Locus Tests into Haplotype Cladistic Analysis in Case-Control Studies
In case-control studies, genetic associations for complex diseases may be probed either with single-locus tests or with haplotype-based tests. Although there are different views on the relative merits and preferences of the two test strategies, haplotype-based analyses are generally believed to be more powerful to detect genes with modest effects. However, a main drawback of haplotype-based ass...
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ژورنال
عنوان ژورنال: PLoS Genetics
سال: 2007
ISSN: 1553-7404
DOI: 10.1371/journal.pgen.0030046