Inappropriate prescribing of proton pump inhibitors in primary care

Inappropriate prescribing of proton pump inhibitors in hospitalized patients.

BACKGROUND Proton pump inhibitors have numerous important side effects, yet they are prescribed for outpatients who do not have recognized indications. Less is known with respect to prescribing for inpatients. OBJECTIVE To determine the rate of inappropriate prescribing of protein pump inhibitors and to assess reasons why they are prescribed. DESIGN AND PARTICIPANTS The study was a retrospe...

Overuse and inappropriate prescribing of proton pump inhibitors in patients with Clostridium difficile-associated disease.

BACKGROUND Clostridium difficile is the most common infectious cause of colitis and has been increasingly diagnosed in hospitalized patients. The number of prescriptions for proton pump inhibitors (PPIs) has also increased significantly over time. Few studies have reported an association between C. difficile-associated disease (CDAD) and PPI use. AIM To assess the extent and appropriateness o...

Inappropriate use of proton pump inhibitors, guidelines and clinical research.

Proton pump inhibitors: a study of GPs' prescribing.

BACKGROUND There has been a rapid increase in proton pump inhibitor (PPI) prescribing in recent years, and controlling the cost and improving the quality of prescribing is an issue of concern to many GPS: OBJECTIVE Our aim was to compare GPs' usage of different PPIs and explore how GPs' PPI prescribing changes following the introduction of a cheaper competitor. METHODS PPI prescribing data ...

Prevalent Prescribing of Proton Pump Inhibitors: Prudent or Pernicious?

ABSTRACT In recent years, the “user-friendly” profile of proton pump inhibitors (PPIs) has resulted in their increased use for a variety of gastrointestinal conditions. Indeed, this trend has been spurred by the profound ability of these agents to decrease gastric acid as well as by their perceived lack of drug interactions and adverse effects. However, recent data suggest possible negative ram...