In VitroEvaluation of Antifungal Drug Combinations against Sarocladium (Acremonium) kiliense, an Opportunistic Emergent Fungus Resistant to Antifungal Therapies

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

In vitro evaluation of antifungal drug combinations against Sarocladium (Acremonium) kiliense, an opportunistic emergent fungus resistant to antifungal therapies.

Sarocladium kiliense, formerly known as Acremonium kiliense (1), is a ubiquitous soil saprophyte commonly found in the environment and occasionally infecting humans (2). Its pathogenicity in immunocompetent patients is low and usually is related to inoculation of the fungus via a penetrating injury that often leads to a granuloma formation. However, the presence of underlying immunological diso...

متن کامل

Alternative approaches to antifungal therapies.

The expansive use of immunosuppressive medications in fields such as transplantational medicine and oncology, the higher frequency of invasive procedures in an ageing population and the HIV/AIDS pandemic have increased the frequency of systemic fungal infections. At the same time, increased resistance of pathogenic fungi to classical antifungal agents has led to sustained research efforts targe...

متن کامل

In vitro activity of antifungal combinations against Candida albicans biofilms.

OBJECTIVES The aim of the present study was to evaluate the in vitro activity and synergism of the combinations of amphotericin B/caspofungin and amphotericin B/posaconazole against Candida albicans, grown either as planktonic cells or in biofilms. METHODS Ten C. albicans bloodstream isolates used in this study were collected from intensive care patients admitted to the Vienna University Hosp...

متن کامل

Antifungal synergy of theaflavin and epicatechin combinations against Candida albicans.

New antifungal agents are required to compensate for the increase in resistance to standard antifungal agents of Candida albicans, which is an important opportunistic fungal pathogen that causes minor infections in many individuals but very serious infections in those who are immune-compromised. In this study, combinations of theaflavin and epicatechin are investigated as potential antifungal a...

متن کامل

Antifungal combinations against Candida albicans biofilms in vitro.

Candida biofilms display increased resistance to most antifungal agents. We have evaluated the efficacy of combinations of fluconazole (FLC), amphotericin B, and caspofungin (CSP) against Candida albicans biofilms in vitro. Indifference was observed for all the combinations of paired antifungal agents when a checkerboard titration method was used. Time-kill experiments revealed an antagonistic ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Antimicrobial Agents and Chemotherapy

سال: 2013

ISSN: 0066-4804,1098-6596

DOI: 10.1128/aac.02131-13