In VitroAntiophidian Mechanisms ofHypericum brasilienseChoisy Standardized Extract: Quercetin-Dependent Neuroprotection

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In Vitro Antiophidian Mechanisms of Hypericum brasiliense Choisy Standardized Extract: Quercetin-Dependent Neuroprotection

The neuroprotection induced by Hypericum brasiliense Choisy extract (HBE) and its main active polyphenol compound quercetin, against Crotalus durissus terrificus (Cdt) venom and crotoxin and crotamine, was enquired at both central and peripheral mammal nervous system. Cdt venom (10 μg/mL) or crotoxin (1 μg/mL) incubated at mouse phrenic nerve-diaphragm preparation (PND) induced an irreversible ...

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ژورنال

عنوان ژورنال: BioMed Research International

سال: 2013

ISSN: 2314-6133,2314-6141

DOI: 10.1155/2013/943520