In vitro HIV-1 infection of human uterine mucosa during pregnancy
نویسندگان
چکیده
منابع مشابه
Antigen-Presenting Cells Represent Targets for R5 HIV-1 Infection in the First Trimester Pregnancy Uterine Mucosa
BACKGROUND During the first trimester of pregnancy, HIV-1 mother-to-child transmission is relatively rare despite the permissivity of placental cells to cell-to-cell HIV-1 infection. The placenta interacts directly with maternal uterine cells (decidual cells) but the physiological role of the decidua in the control of HIV-1 transmission and whether decidua could be a source of infected cells is...
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Management of HIV infection during pregnancy.
Optimal management of HIV infection in pregnancy requires maternal use of potent antiretroviral therapy to prevent disease progression in the mother and vertical transmission to the newborn. Combination antiretroviral therapy substantially reduces the risk of perinatal HIV transmission and appears to be more effective than zidovudine monotherapy. The administration of single dose nevirapine to ...
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ژورنال
عنوان ژورنال: Retrovirology
سال: 2008
ISSN: 1742-4690
DOI: 10.1186/1742-4690-5-s1-p7