In-vitro genetic modification of mitochondrial function
نویسندگان
چکیده
منابع مشابه
In-vitro genetic modification of mitochondrial function.
Defects of mitochondrial (mt) DNA cause a diverse group of incurable, progressive diseases that often lead to severe disability and premature death. Most patients with pathogenic mtDNA defects have a mixture of mutant and wild-type mtDNA (heteroplasmy), and the clinical defect is only expressed when the percentage of mutant mtDNA exceeds a critical threshold. Since mtDNA is continually replicat...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 2000
ISSN: 0268-1161,1460-2350
DOI: 10.1093/humrep/15.suppl_2.79