In Vitro Dissolution Curve Comparisons: A Critique of Current Practice

In Vitro Dissolution Curve Comparisons: A Critique of Current Practice

Many pharmacologically active molecules are formulated as solid dosage form drug products. Following oral administration, the diffusion of an active molecule from the gastrointestinal tract into systemic distribution requires the disintegration of the dosage form followed by the dissolution of the molecule in the stomach lumen. Its dissolution properties may have a direct impact on its bioavail...

Comparisons of in vitro propagation of tomato cultivars

Current state of bone scintigraphy protocols and practice in Japan

Objective(s): Nuclear medicine technologists in Japan often perform additional single-photon emission computed tomography (SPECT) with or without computed tomography (CT) after whole-body imaging for bone scintigraphy. In this study, we wanted to identify the bone scanning protocols used in Japan, together with the current clinical practices. Methods:...

Homeopathy: A Critique of Current Clinical Research

Homeopathy has remained one of the most controversial medical treatments in the world. It is based on the “like cures like” principle and the idea that serial dilution of a substance renders it not less but more potent. Both of these axioms of homeopathy lack biological plausibility (Sehon and Stanley 2010). Nevertheless, homeopathy was recently cited as one of “the most popular and widely used...

Material Practice as a Form of Critique

The paper characterizes how material practice becomes a form of critique. Based on a comparison of two presumably distant objects, it delineates how engagement with materiality opposes established forms of knowledge production and representation. One object is a robotic hand, which is made of silicon, and the other object is a media art installation that transforms signals of the Earth’s magnet...