In Vitro Comparison of the Antimicrobial Effects of Different Root Canal Medicaments on Enterococcus faecalis and Candida albicans

Objectives: To evaluate the antimicrobial effects of experimental root canal medicaments on Enterococcus faecalis and Candida albicans day 3 7 using quantitative polymerase chain reaction (Q-PCR) analyses. Materials Methods: 240 single-rooted, single-canalled human teeth were used. Root canals shaped mechanically embedded in acrylic blocks, then sterilized an autoclave. The samples divided into two groups infected with E. C. albicans, subgroups (n=10); calcium hydroxide (Ca(OH)2), triple paste (TAP), double (DP), modified (MDP), lactoferrin (Lf), negative positive groups. At end days, paper points containing placed empty Eppendorf tubes, DNA was isolated. Real-time Q-PCR applied data analyzed statistically. Results: each medicine increased from days to 7. Ca(OH)2 TAP showed similar eradication rates for (P > 0.05). There no significant difference between DP, MDP Lf microorganisms at both 0.05), except amount eradicated by DP which caught percentages < Conclusions: Experimental pastes demonstrated efficiancy those used routinely endodontic clinic. It is promising that a very biocompatible material can be different combinations as intracanal medicament.