In vitro cell growth in neonates with Down's syndrome and transient myeloproliferative disorder
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چکیده
منابع مشابه
In vitro cell growth in neonates with Down's syndrome and transient myeloproliferative disorder.
Bone marrow and peripheral blood cells from three newborns with Down's syndrome and transient myeloproliferative disorders were cultured in vitro. In the methylcellulose semiliquid system, normal colony formation with maturation and differentiation into granulocytes and monocyte-macrophages were observed in all three patients. This is different from the growth pattern usually seen in acute nonl...
متن کاملDown's syndrome with transient myeloproliferative disorder.
Children with Down's syndrome are at an increased risk for development of several hematological disorders like acute leukemia, acute myelofibrosis of childhood and transient myeloproliferative disorder (TMD)(1). Transient myeloproliferative disorder is recognized shortly after birth or in neonatal period and is characterized by leukocytosis and thrombocytopenia, which resolves spontaneously in ...
متن کاملTransient Myeloproliferative Disorder in Neonate with Suspected Down Syndrome
A female with suspected Down syndrome was born by vaginal delivery at 37 weeks 2 days’ gestation to a mother with a history of Type A2 gestational diabetes mellitus. Routine prenatal testing consisted of a non-invasive screening test for aneuploidy. Results, presented in Table 1, indicated an aneuploidy for trisomy of chromosome 21, indicating an increased risk for Down syndrome. Prenatal confi...
متن کاملTransient myeloproliferative syndrome associated with Down syndrome.
production run with hydrogen peroxide and rinsed with deionized water. As moisture may remain in the less accessible points of the system (bends and filters), Kathon CG is added to the rinse water to ensure a completely sterile process. As a result of this finding, the company marketing the cream compensated the patient and changed the procedure for cleaning the machinery, replacing the Kathon ...
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Transient myeloproliferative disorder is a hematological condition observed during the neonatal period in patients with Down syndrome [1]. This disorder mimics congenital leukemia and the blast cells were often reported to show characteristics compatible with those of megakaryoblasts [2] or pluripotent stem cells [3]. Although this disorder usually resolves gradually without antileukemic treatm...
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ژورنال
عنوان ژورنال: Blood
سال: 1981
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v58.4.675.675