In Vitro Anti-Inflammatory Potential of Anaphyllum wightii Schott: An Endemic Plant of Southern Western Ghats

Inflammation is a protective mechanism offered by the body’s immune system after an injury, microbial infection, or any other physical chemical damage. The role of cyclooxygenase and lipoxygenase enzymes in inflammation process has been well established, research works are focused on developing plant-based inhibitors that can provide potential anti-inflammatory drugs with no side effects. Even though there previous reports suggesting rhizome plant, available regarding property leaves Anaphyllum wightii. Hence present study was intended to assess activity wightii also confirm vitro. action two morphological variants (broad narrow leaves) were determined their inhibitory effects enzymes. In case inhibition assay, leaf extract showed least IC50 value (43.182 µg/ml), whereas broad (38.174 µg/ml) for enzyme. Thus revealed extracts exhibit significant compared extract. may contain promising agents treating chronic inflammatory diseases. Also, this could detect presence Ursolic acid, agent, through high resolution liquid chromatograph mass spectrometeric performance thin layer chromatographic analyses.