منابع مشابه
In utero repair of fetal rat myelomeningocele affects neuromuscular development in the bladder
Fetal repair of myelomeningocele (MMC) has been proven to be beneficial for the central nervous system development; however, the effect of fetal MMC repair on bladder function remains controversial. The objective of the present study was to establish an early timepoint for in utero MMC repair using a rat model, and to investigate the changes in bladder development subsequent to that interventio...
متن کاملIn utero Repair of Myelomeningocele: Rationale, Initial Clinical Experience and a Randomized Controlled Prospective Clinical Trial.
Myelomeningocele (MMC), one of the most common congenital malformations, can result in severe lifelong disabilities, including paraplegia, hydrocephalus, Arnold-Chiari II malformation, incontinence, sexual dysfunction, skeletal deformations, and mental impairment. MMC was the first nonlethal anomaly to be treated by fetal surgery. Studies in animals provide compelling evidence that the primary ...
متن کاملIn utero myelomeningocele repair: baby steps and giant leaps for fetal surgery.
1016 May 2013 A FTER decades of preparing the theoretical framework of fetal surgery,1 the reality of it finally hit home in 2011 when Adzick et al. published their National Institutes of Health-supported study on outcomes after in utero surgery for myelomeningocele. Aptly named MOMS (Management of Myelomeningocele Study), the investigators terminated enrollment early after demonstrating that c...
متن کاملLarge myelomeningocele repair
BACKGROUND Wound closure is accomplished in most cases of myelomeningocele (MMC) by undermining of the skin edges surrounding the defect. However, large defects cannot be closed reliably by this simple technique. Due to the technical challenge associated with large MMC, surgeons have devised different methods for repairing large defects. In this paper, we report our experience of managing large...
متن کاملAnaesthetic Challenges and Management of Myelomeningocele Repair
IntroductIon: Failure of neural tube closure early in intrauterine development results in spectrum of abnormalities ranging from spinabifidaocculta, a relativelybenigncondition to meningomyeocele, an abnormality involving vertebral bodies, spinal cord and brainstem. These babies also have associated congenital anomaliese.g.intestinalmalrotation, renal anomalies, cardiac malformations and trache...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Archives of Surgery
سال: 2003
ISSN: 0004-0010
DOI: 10.1001/archsurg.138.8.872