In Situ Forming Injectable Thermoresponsive Hydrogels for Controlled Delivery of Biomacromolecules
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چکیده
منابع مشابه
Preparation and Characterization of Thermoresponsive In-situ Forming Poloxamer Hydrogel for Controlled Release of Nile red-loaded Solid Lipid Nanoparticles
Preparation and characterization of thermoresponsive in-situ forming poloxamer hydrogel for controlled release of Nile red-loaded solid lipid nanoparticles. Nanoparticles (NPs) are cleared rapidly from systemic circulation and do not provide sustained action in most cases. To solve this problem, this investigation introduces an erodible in-situ forming gel system as potential vehicles for prolo...
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AbstractVarious nanoparticles have been investigated as novel drug delivery systems, including solid lipid nanoparticles (SLNs). Due to their rapid clearance from systemic circulation, nanoparticles do not provide sustained action in most cases. Different strategies have been employed to overcome this problem. In this direction, the present study introduces erodible in-situ forming gel systems ...
متن کاملPreparation of SLN-containing Thermoresponsive In-situ Forming Gel as a Controlled Nanoparticle Delivery System and Investigating its Rheological, Thermal and Erosion Behavior
AbstractVarious nanoparticles have been investigated as novel drug delivery systems, including solid lipid nanoparticles (SLNs). Due to their rapid clearance from systemic circulation, nanoparticles do not provide sustained action in most cases. Different strategies have been employed to overcome this problem. In this direction, the present study introduces erodible in-situ forming gel systems ...
متن کاملInjectable in situ cross-linking hydrogels for local antifungal therapy.
Invasive fungal infections can be devastating, particularly in immunocompromised patients, and difficult to treat with systemic drugs. Furthermore, systemic administration of those medications can have severe side effects. We have developed an injectable local antifungal treatment for direct administration into existing or potential sites of fungal infection. Amphotericin B (AmB), a hydrophobic...
متن کاملpreparation and characterization of thermoresponsive in-situ forming poloxamer hydrogel for controlled release of nile red-loaded solid lipid nanoparticles
preparation and characterization of thermoresponsive in-situ forming poloxamer hydrogel for controlled release of nile red-loaded solid lipid nanoparticles. nanoparticles (nps) are cleared rapidly from systemic circulation and do not provide sustained action in most cases. to solve this problem, this investigation introduces an erodible in-situ forming gel system as potential vehicles for prolo...
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ژورنال
عنوان ژورنال: ACS Omega
سال: 2020
ISSN: 2470-1343,2470-1343
DOI: 10.1021/acsomega.0c02009