In Situ Capture of Bacterial Toxins for Antivirulence Vaccination
نویسندگان
چکیده
منابع مشابه
Newly discovered and characterized antivirulence compounds inhibit bacterial mono-ADP-ribosyltransferase toxins.
The mono-ADP-ribosyltransferase toxins are bacterial virulence factors that contribute to many disease states in plants, animals, and humans. These toxins function as enzymes that target various host proteins and covalently attach an ADP-ribose moiety that alters target protein function. We tested compounds from a virtual screen of commercially available compounds combined with a directed poly(...
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ژورنال
عنوان ژورنال: Advanced Materials
سال: 2017
ISSN: 0935-9648,1521-4095
DOI: 10.1002/adma.201701644