In silico studies of solvated F19W amyloid β (11–40) trimer
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چکیده
منابع مشابه
The Resveratrol Trimer Miyabenol C Inhibits β-Secretase Activity and β-Amyloid Generation
Accumulation and deposition of amyloid-β peptide (Aβ) in the brain is a primary cause of the pathogenesis of Alzheimer's disease (AD). Aβ is generated from amyloid-β precursor protein (APP) through sequential cleavages first by β-secretase and then by γ-secretase. Inhibiting β-secretase activity is believed to be one of the most promising strategies for AD treatment. In the present study, we fo...
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ژورنال
عنوان ژورنال: RSC Advances
سال: 2017
ISSN: 2046-2069
DOI: 10.1039/c7ra07187f