In silico studies of bacterial quorum sensing during population dynamics: simulations by using COMSOL Multiphysics

Abstract In the present study, computing techniques are designated and employed in order to analyze “quorum sensing” as a special case of cell-to-cell bacterial communication attributed Pseudomonas genus. One challenges consists predicting concentration key substances characterizing level” during population dynamics. To estimate relevant characteristics communication, we applied deterministic approach. The mathematical model is formalized an initial-boundary value problem for system semilinear partial differential equations supplemented by procedure specify multiphase dynamics populations. finite element solution obtained COMSOL Multiphysics. comparative numerical analysis various types space approximation density performed. A series computational experiments were conducted changes concentrations chemical compounds putida