منابع مشابه
Ofatumumab Monoclonal Antibody Affinity Maturation Through in silico Modeling
Background: Ofatumumab, an anti-CD20 mAb, was approved in 2009 for the treatment of chronic lymphocytic leukemia. This mAb acts through immune-mediated mechanisms, in particular complement-dependent cytotoxicity and antibody-dependent cellular cytotoxicity by natural killer cells as well as antibody-dependent phagocytosis by macrophages. Apoptosis induction is another mechanism of this antibody...
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Increased susceptibility of birds to avian pathogens in intensive husbandry system has emphasized on necessity of improvement of innate and specific immune responses of birds by the fast establishment of a beneficial microflora and immune stimulator factors to guarantee healthy and low-price products. During this study, 192 one-day-old broiler chicks (Ross-380) in four groups with three replica...
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Brian H. Feighner, Stephen Eubank, Robert J. Glass, Victoria J. Davey, Jean-Paul Chrétien, and Joel C. Gaydos Author affiliations: The Johns Hopkins University Applied Physics Laboratory, Laurel, Maryland, USA (B.H. Feighner); Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA (S. Eubank); Sandia National Laboratories, Albuquerque, New Mexico, USA (R.J. Glass); US De...
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Over the last years, an intensive worldwide effort is speeding up the developments in the establishment of a global surveillance network for combating pandemics of emergent and re-emergent infectious diseases. Scientists from different fields extending from medicine and molecular biology to computer science and applied mathematics have teamed up for rapid assessment of potentially urgent situat...
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Many behavioral phenomena have been found to spread interpersonally through social networks, in a manner similar to infectious diseases. An important difference between social contagion and traditional infectious diseases, however, is that behavioral phenomena can be acquired by non-social mechanisms as well as through social transmission. We introduce a novel theoretical framework for studying...
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ژورنال
عنوان ژورنال: Drug Discovery Today: Disease Models
سال: 2007
ISSN: 1740-6757
DOI: 10.1016/j.ddmod.2007.09.001