In silico methods for co-transcriptional RNA secondary structure prediction and for investigating alternative RNA structure expression
نویسندگان
چکیده
منابع مشابه
RNA Secondary Structure Prediction.
In this unit, protocols are provided for predicting RNA secondary structure with the user-friendly RNAstructure desktop computer program and the RNAstructure Web server. The minimum free energy structure and a set of suboptimal structures with similar free energies are predicted. Prediction of high-affinity oligonucleotide binding sites to a structured RNA target is also presented. © 2016 by Jo...
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Understanding secondary structures of RNAs helps to determine their chemical and biological properties. Only a small number of RNA structures have been determined currently since such structure determination experiments are timeconsuming and expensive. As a result, scientists start to rely on RNA secondary structure prediction. Unlike protein structure prediction, predicting RNA secondary struc...
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RNA secondary structure prediction is an area of bioinformatics that is the subject of significant amounts of research; it is the process of turning a sequence of bases on an RNA strand, for example, AUGUAGCAUC into a map of the interactions between the base pairs. This report looks at different methods of approaching this problem using dynamic programming algorithms. Nussinov’s algorithm was u...
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The prediction of RNA structure is useful for understanding evolution for both in silico and in vitro studies. Physical methods like NMR studies to predict RNA secondary structure are expensive and difficult. Computational RNA secondary structure prediction is easier. Comparative sequence analysis provides the best solution. But secondary structure prediction of a single RNA sequence is challen...
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ژورنال
عنوان ژورنال: Methods
سال: 2017
ISSN: 1046-2023
DOI: 10.1016/j.ymeth.2017.04.009