In Silico Analysis of Functional Single Nucleotide Polymorphisms in the Human TRIM22 Gene
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چکیده
منابع مشابه
In Silico Analysis of Functional Single Nucleotide Polymorphisms in the Human TRIM22 Gene
Tripartite motif protein 22 (TRIM22) is an evolutionarily ancient protein that plays an integral role in the host innate immune response to viruses. The antiviral TRIM22 protein has been shown to inhibit the replication of a number of viruses, including HIV-1, hepatitis B, and influenza A. TRIM22 expression has also been associated with multiple sclerosis, cancer, and autoimmune disease. In thi...
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Lymphedema is an abnormal accumulation of interstitial fluid, Introduction due to inefficient uptake and reduced flow, leading to swelling and disability, mostly in the extremities. Hereditary lymphedema usually occurs as an autosomal dominant trait with allelic heterogeneity. : We identified single nucleotide polymorphisms (SNPs) in the FOXC2 Methods gene using dbSNP, analyzed their effect on ...
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Lymphedema is abnormal accumulation of interstitial fluid, due to Introduction inefficient uptake and reduced flow, leading to swelling and disability, mostly in the extremities. Hereditary lymphedema usually occurs as an autosomal dominant trait with allelic heterogeneity. We identified single Methods: nucleotide polymorphisms (SNPs) in the FOXC2 gene using dbSNP, analyzed their effect on the ...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2014
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0101436