In 2035, will all bacteria be multidrug-resistant? No

Multidrug-Resistant Bacteria in Southeastern Austria

To the Editor: In many parts of the world, the proportions of methicil-lin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant en-terococci, and extended-spectrum β-lactamase (ESBL)–producing organisms in the family Enterobacteriaceae have increased remarkably during recent years (1). However, proportions of antimicrobial drug resistance vary substantially at national and regional leve...

Prospects for Success in Inhibiting the Growth of Multidrug-resistant Bacteria with Paromomycin

Streptomyces is the most important bacterial genus known to produce secondary antibiotic compounds. Considering the speed of bacterial resistance spread, it becomes more important to study less used compounds. Aminoglycosides disrupt the function of the target microorganism by acting on the protein-synthesis process. Paromomycin is an aminoglycoside that acts on a wide range of gram-positive, g...

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Multidrug-resistant bacteria: what is the threat?

Despite big advances in antimicrobial therapies and infection strategies, the emergence of antibiotic resistance represents an emergency situation, especially in immunocompromised hosts. Specifically, infections due to multidrug resistant, gram-negative pathogens are responsible for high mortality rates and may leave few effective antimicrobial options. Furthermore, although new compounds are a...

Tomorrow's library: will it all be infrastructure?

The form in which knowledge is described and encapsulated has a major impact on the design of libraries and the functions performed within the library. Libraries as we known them have been primarily built to store and disseminate knowledge in book format. New technology and the changing needs of knowledge workers, which form important parts of the logocentric, practicentric, and democentric ele...