IMUNITAS ALAMIAH: EOSINOPHIL EXTRACELLULAR TRAPS (EET)
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چکیده
منابع مشابه
Highlight : Eosinophil extra - cellular traps in Allergy
Eosinophil degranulation has always aroused the interests of physicians and scientists alike. Loss of viability and release of membrane-free granules upon eosinophil degranulation was first demonstrated by Gleich and coworkers in 1996. These free eosinophil granules, once considered as crush artifacts, are now confirmed products of eosinophil cytolysis, and suggested to be significantly pathoge...
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Cancers prime neutrophils to release extracellular DNA traps through the systemic release of granulocyte colony-stimulating factor (G-CSF). We recently showed that these circulating neutrophil extracellular traps (NETs) promote the establishment of a pro-thrombotic state. The role of NETs in cancer biology and tumor progression may prove much more than an unfortunate side effect of cancer.
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Coming soon to a doctor’s surgery near you? Hopes placed on the sequencing of ‘the’ human genome and the subsequent identification of many single-nucleotide polymorphisms (SNPs) have turned out to be misguided, as the causes of common diseases like cancer and heart disease have proven too complex to be addressed with simple SNP searches. Also, large-scale genomic differences like copy number va...
متن کاملNicotine induces neutrophil extracellular traps.
NETs serve to ensnare and kill microbial pathogens. However, NETs can at the same time contribute to tissue damage and excessive inflammation. Nicotine is a major toxic agent and has been associated with exacerbated inflammatory diseases. The current study aimed at investigating the role of nicotine, the addictive component of tobacco and electronic cigarettes, on triggering NET formation. We r...
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Neutrophils are the most numerous immune cells. Their importance as the first line of defense against bacterial and fungal pathogens is well described. In contrast, the role of neutrophils in controlling viral infections is less clear. Bacterial and fungal pathogens can stimulate neutrophils extracellular traps (NETs) in a process called NETosis. Although NETosis has previously been described a...
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ژورنال
عنوان ژورنال: Biomedika
سال: 2015
ISSN: 2541-2582,2085-8345
DOI: 10.23917/biomedika.v5i1.272