Improved methods for blastocyst formation and culture
نویسندگان
چکیده
منابع مشابه
Improved methods for blastocyst formation and culture.
Transfer at the blastocyst stage has been proposed to increase the pregnancy rates after in-vitro fertilization (IVF) and embryo transfer. In the first period of experiments, culture in a single medium, from fertilization to blastocyst led to disappointing results: low blastocyst formation rates and low implantation rates per blastocyst transferred. Then the period of co-culture began (starting...
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Both cleavage-stage and blastocyst-stage embryo transfer policieshave advantages and drawbacks.Potential advantages of blastocyst culture and transfer in human IVF include: i. synchronization of the embryo with the female tract leading to increasedimplantation rates; thereby, reducing the need for multipleembryo transfers, ii. assessment of viability of an embryobefore transfer. This can be ach...
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It should now be beyond doubt that blastocyst culture results in better pregnancy rate (PR). This calls for fewer embryos to be transferred, and indeed blastocyst culture is of most value when the intention is to put back one embryo at a time. The PR with one top-grade blastocyst is 45-65% in different studies. If two top-grade blastocysts are transferred, the PR usually does not differ, but th...
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Blastocyst culture: facts and fiction.
The use of sequential media has made extended culture and transfer of blastocysts feasible for human IVF. Embryo transfer on day 5 has been claimed to result in higher implantation rates than transfer on day 3, on the basis of retrospective comparative studies. This is not supported convincingly, however, in randomized controlled trials published to date. Blastocyst culture imposes additional r...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 1998
ISSN: 0268-1161,1460-2350
DOI: 10.1093/humrep/13.suppl_4.256