Impediment of selenite-induced cataract in rats by combinatorial drug laden liposomal preparation
نویسندگان
چکیده
منابع مشابه
Hesperetin prevents selenite-induced cataract in rats
PURPOSE This study investigated the ability of hesperetin, a natural flavonoid, to prevent selenite-induced cataracts in a rat model. METHODS Animals were divided into four treatment groups: G1 (control group), G2 (hesperetin-treated group), G3 (selenite-induced cataract group), and G4 (hesperetin-treated selenite cataract group). Animals in the G1 and G3 groups were injected with vehicle alo...
متن کاملEffect of Aqueous Extract of Embelica officinalis on Selenite Induced Cataract in Rats
Cataract is clouding of the eye lens that reduces the amount of incoming light and results in deteriorating vision. Blindness is thought to reach 75 million by 2020. Of these, unoperated cataract may be expected to account for at least 35 million. Thus, the burden of cataract is increasing remorselessly. Embelica officinalis is reported to have a very good antioxidant property and thus we hypot...
متن کاملEffect of Aqueous Extract of Embelica officinalis on Selenite Induced Cataract in Rats
Cataract is clouding of the eye lens that reduces the amount of incoming light and results in deteriorating vision. Blindness is thought to reach 75 million by 2020. Of these, unoperated cataract may be expected to account for at least 35 million. Thus, the burden of cataract is increasing remorselessly. Embelica officinalis is reported to have a very good antioxidant property and thus we hypot...
متن کاملHydrogen saline prevents selenite-induced cataract in rats
PURPOSE The aim of this study was to investigate the potential antioxidative effect and mechanism for the protective effects of hydrogen saline on selenite-induced cataract in rats. METHODS Sprague-Dawley rat pups were divided into the following groups: control (Group A), selenite induced (Group B), and selenite plus hydrogen saline treated (Group C). Rat pups in Groups B and C received a sin...
متن کاملDeferoxamine effect on selenite-induced cataract formation in rats.
A single subcutaneous dose of 30 nmol of sodium selenite per gram of body weight in 13-day-old rats resulted in posterior subcapsular cataract (PSC) after 24 hr and bilateral nuclear cataracts at 72-96 hr. Within 24 hr of treatment, a 60% decrease in lens glutathione was seen. A loss of calcium homeostasis observed by 48 hr resulted in increased lens calcium (4 mumol/g dry weight), which accomp...
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ژورنال
عنوان ژورنال: Libyan Journal of Medicine
سال: 2018
ISSN: 1993-2820,1819-6357
DOI: 10.1080/19932820.2018.1548252