Impaired Preadipocyte Differentiation Into Adipocytes in Subcutaneous Abdominal Adipose of PCOS-Like Female Rhesus Monkeys
نویسندگان
چکیده
منابع مشابه
Impaired Preadipocyte Differentiation in Human Abdominal Obesity
OBJECTIVE We examined preadipocyte differentiation in obese and nonobese individuals and the effect of cytokines and wingless-type MMTV (mouse mammary tumor virus) integration site family, member 3A (Wnt3a) protein on preadipocyte differentiation and phenotype. RESEARCH DESIGN AND METHODS Abdominal subcutaneous adipose tissue biopsies were obtained from a total of 51 donors with varying BMI. ...
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Expansion of adipose tissue mass results from increased number and size of adipocyte cells. We hypothesized that subcutaneous abdominal preadipocytes in obese individuals might have an intrinsically higher propensity to differentiate into adipocytes. Thus we investigated the relationship between obesity and the level of in vitro preadipocyte differentiation in Pima Indians. Subcutaneous abdomin...
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ژورنال
عنوان ژورنال: Endocrinology
سال: 2014
ISSN: 0013-7227,1945-7170
DOI: 10.1210/en.2014-1050