Impaired glucose homeostasis in insulin-like growth factor-binding protein-3-transgenic mice
نویسندگان
چکیده
منابع مشابه
Impaired glucose homeostasis in insulin-like growth factor-binding protein-3-transgenic mice.
Glucose homeostasis was examined in male transgenic (Tg) mice that overexpressed the human insulin-like growth factor (IGF)-binding protein (IGFBP)-3 cDNA, driven by either the cytomegalovirus (CMV) or the phosphoglycerate kinase (PGK) promoter. The Tg mice of both lineages demonstrated increased serum levels of human (h) IGFBP-3 and total IGF-I compared with wild-type (Wt) mice. Fasting blood ...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Endocrinology and Metabolism
سال: 2002
ISSN: 0193-1849,1522-1555
DOI: 10.1152/ajpendo.00014.2002