Impaired Endothelial-Dependent and Endothelium-Independent Vasodilatation in Patients With Thromboangiitis Obliterans
نویسندگان
چکیده
منابع مشابه
Endothelium-dependent vasodilatation in forearm is impaired in stroke patients.
OBJECTIVES To investigate endothelium-dependent vasodilatation (EDV) in stroke patients. DESIGN Cross-sectional. SETTING University referral hospital. SUBJECTS We studied 23 stroke patients (65-75 years old) who did not have atrial fibrillation or Warfarin treatment. Forty-six age- and sex-matched healthy controls and another 32 controls matched also for hypertension and medication were u...
متن کاملDysfunctional endothelial nitric oxide biosynthesis in healthy smokers with impaired endothelium-dependent vasodilatation.
BACKGROUND The mechanisms involved in the dysfunction of both endothelium-dependent vasodilatation (EDV) and NO biosynthesis related to smoking are unclear. In this study, EDV was assessed in healthy smokers and nonsmokers in vivo and, using serum from the same individuals, was related to the NO biosynthetic pathway in vitro. METHODS AND RESULTS Flow-mediated EDV of the brachial artery was me...
متن کاملThromboangiitis obliterans with cryoglobulinemia.
Thromboangiitis obliterans (TAO), or Buerger's disease, is a vascular occlusive disease associated with cigarette smoking. It typically affects medium sized vessels of extremities. Basic pathology of TAO is described to be endothelial activation with highly inflammatory intraluminal thrombosis preserving internal elastic membrane. Cryoglobulins are immunoglobulins that precipitate in the cold a...
متن کاملThromboangiitis obliterans.
Case presentation: A 39-year-old male smoker with a 2-year history of calf discomfort on ambulation culminating in left femoral-to-peroneal artery bypass presented with right leg discomfort and recurrent painful subcutaneous nodules on his feet and calves. Biopsy of a nodule from his right foot was interpreted as vasculitis with thrombosis and fibrinoid necrosis in subcutaneous vessels, and the...
متن کاملThromboangiitis obliterans.
Thromboangiitis obliterans (TAO) has been a recognized clinical entity for more than half a century (Buerger, 1908). Distal arterial occlusive disease and/or recurrent superficial thrombophlebitis occurring in an adult male smoker, in the absence of known cause, constitutes a distinctive and unmistakable syndrome (Brown, Allen, and Mahorner, 1928). However, the existence of this disorder has be...
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ژورنال
عنوان ژورنال: Clinical and Applied Thrombosis/Hemostasis
سال: 2012
ISSN: 1076-0296,1938-2723
DOI: 10.1177/1076029611435093