Impaired diaphragm resistance vessel vasodilation with prolonged mechanical ventilation
نویسندگان
چکیده
منابع مشابه
[Prolonged mechanical ventilation probability model].
OBJECTIVE To design a probability model for prolonged mechanical ventilation (PMV) using variables obtained during the first 24 hours of the start of MV. DESIGN An observational, prospective, multicenter cohort study. SCOPE Thirteen Spanish medical-surgical intensive care units. PATIENTS Adult patients requiring mechanical ventilation for more than 24 hours. INTERVENTIONS None. STUDY ...
متن کاملEffect of mechanical ventilation on the diaphragm.
It is widely assumed that respiratory-muscle weakness, either intrinsic or due to fatigue, leads to respiratory failure.1 For the past 30 years, attention has been focused on whether the diaphragm muscle is especially susceptible to fatigue in patients with chronic pulmonary disease and critical illness, increasing the potential for respiratory failure.2,3 In the 1980s and early 1990s, this con...
متن کاملAltered diaphragm contractile properties with controlled mechanical ventilation.
This study shows that, over time, diaphragm inactivity with controlled mechanical ventilation (CMV) decreases diaphragm force and produces myofibril damage contributing to the reduced force. We measured in vivo and in vitro diaphragm contractile and morphological properties in 30 sedated rabbits grouped (n = 6) as follows: 1 or 3 days of CMV, 1 or 3 days of 0 cmH(2)O continuous positive airway ...
متن کاملPatterns of diaphragm function in critically ill patients receiving prolonged mechanical ventilation: a prospective longitudinal study
BACKGROUND In intensive care unit (ICU) patients, diaphragmatic dysfunction (DD) can occur on admission or during the subsequent stay. The respective incidence of these two phenomena has not been previously studied in humans. The study was designed to describe temporal trends in diaphragm function in mechanically ventilated (MV) patients. METHODS Ancillary study of a prospective, 6-month, obs...
متن کاملEarly changes in rat diaphragm biology with mechanical ventilation.
To better characterize the effects of 24-hour mechanical ventilation on diaphragm, the expression of myogenic transcription factors, myosin heavy chains, and sarcoplasmic/endoplasmic reticulum calcium-ATPase pumps was examined in rats. In the diaphragm of mechanically ventilated animals, the mRNA of MyoD, myosin heavy chain-2a and -2b, and sarcoplasmic/endoplasmic reticulum calcium-ATPase-1a de...
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ژورنال
عنوان ژورنال: Journal of Applied Physiology
سال: 2019
ISSN: 8750-7587,1522-1601
DOI: 10.1152/japplphysiol.00189.2019