Impact of real-time, dose-escalated permanent seed implant brachytherapy in intermediate-risk prostate cancer

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High dose brachytherapy (real time) in patients with intermediate- or high-risk prostate cancer: technical description and preliminary experience.

INTRODUCTION It has been well documented that the outcome of prostate cancer treatment depends on the dose administered. Hence, techniques have been developed that allow high-dose administration without increasing the complications, e.g. external radiotherapy combined with high-dose radiation (HDR) brachytherapy. In this article we analyse the technique and protocol of real-time HDR brachythera...

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INTRODUCTION We sought to compare the outcomes between radical prostatectomy (RP) and permanent seed prostate brachytherapy (PB) in patients with low- and low-intermediate-risk prostate cancer from a single tertiary care centre. METHODS Patients were selected from our institute's internal database based on preoperative selection criteria from the National Comprehensive Cancer Network (NCCN) g...

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Inverse planning optimization for hybrid prostate permanent‐seed implant brachytherapy plans using two source strengths

The purpose is to demonstrate the ability to generate clinically acceptable prostate permanent seed implant plans using two seed types which are identical except for their activity. The IPSA inverse planning algorithms were modified to include multiple dose matrices for the calculation of dose from different sources, and a selection algorithm was implemented to allow for the swapping of source ...

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Transperineal Permanent Brachytherapy of Localised Prostate Cancer

Context: In absence of prospective randomized trials determining the optimal management of localized prostate cancer remains undefined. Objective: To develop and disseminate an update on outcome of different treatment modalities, recommendations and guidelines of transperineal prostate brachytherapy. Evidence acquisition: In the past decade, the average number of brachytherapy patients per cent...

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ژورنال

عنوان ژورنال: Reports of Practical Oncology & Radiotherapy

سال: 2020

ISSN: 1507-1367

DOI: 10.1016/j.rpor.2020.04.014