Impact of hypoglycemic agents on myocardial ischemic preconditioning
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چکیده
منابع مشابه
Myocardial apoptosis and ischemic preconditioning.
Necrosis and apoptosis are two forms of cell death in the myocardium that have been associated with ischemia and reperfusion. Although it has been well documented that necrosis, as a major form of myocyte cell death, rapidly leads to a destruction of a large group of cells after myocardial ischemia and reperfusion, the induction of apoptosis in myocardium, primarily triggered during reperfusion...
متن کاملEffect of Hypoglycemic Agents on Ischemic Preconditioning in Patients With Type 2 Diabetes and Symptomatic Coronary Artery Disease
OBJECTIVE To assess the effect of two hypoglycemic drugs on ischemic preconditioning (IPC) patients with type 2 diabetes and coronary artery disease (CAD). RESEARCH DESIGN AND METHODS We performed a prospective study of 96 consecutive patients allocated into two groups: 42 to group repaglinide (R) and 54 to group vildagliptin (V). All patients underwent two consecutive exercise tests (ET1 and...
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OBJECTIVES We attempted to establish whether naloxone, an opioid receptor antagonist, abolishes the adaptation to ischemia observed in humans during coronary angioplasty after repeated balloon inflations. BACKGROUND Experimental studies indicate that myocardial opioid receptors are involved in ischemic preconditioning. METHODS Twenty patients undergoing angioplasty for an isolated stenosis ...
متن کاملEffects of ischemic preconditioning on myocardial protective on cardiac surgery: possibility of ischemic preconditioning and adenosine administration.
SUBJECT We evaluated the efficacy for concomitant use of ischemic preconditioning (IPC) and cardioplegic arrest with adenosine premedication on myocardial protection. METHODS Twenty-one pigs were divided into three groups: 1) control group, 2) IPC group which had IPC, 3) IPC+adenosine triphosphate (ATP) group which had an administration of 140 gamma of ATP (Adetphos, Kowa, Tokyo, Japan) durin...
متن کاملIschemic Preconditioning Increases Myocardial Tolerance to Subsequent Ischemic Episodes
It has long been recognized that a brief episode of myocardial ischemia causes reversible myocyte injury, "reversible" being defined by the fact that early restoration of arterial flow prevents infarction and permits eventual restoration of normal myocardial structure, function, and metabolism. However, numerous studies during the last 15 years1-5 have revealed that complete recovery is not imm...
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ژورنال
عنوان ژورنال: World Journal of Diabetes
سال: 2014
ISSN: 1948-9358
DOI: 10.4239/wjd.v5.i3.258