Impact of hydrosalpinx fluid on early human embryos
نویسندگان
چکیده
منابع مشابه
Hydrosalpinx fluid does not adversely affect the normal development of human embryos and implantation in vitro.
Several retrospectively designed studies have shown an association between the presence of hydrosalpinx and impaired implantation and pregnancy rates among in-vitro fertilization (IVF) patients. In the present study we have evaluated the influence of hydrosalpinx fluid on normal human embryo development and implantation. Surplus, donated frozen embryos (n = 183) from IVF patients were used to s...
متن کاملIs hydrosalpinx fluid cytotoxic?
Accumulation of oviductal fluid in the ampullar lumen as a result of occlusion of the infundibulum is referred to as hydrosalpinx. A low pregnancy rate (10%) after in-vitro fertilization (IVF) in hydrosalpinx patients and a relatively high incidence (50%) of abortions during the first trimester suggested that leakage of this fluid into the uterine cavity may exert a cytotoxic effect on the deve...
متن کاملAdverse effects of hydrosalpinx fluid on sperm motility and survival.
The negative impact of hydrosalpinx on IVF outcome is well recognized but some reports indicate that tubal infertility with hydrosalpinx is a heterogeneous entity and may have different effects on the outcome. The embryotoxic effects of hydrosalpinx fluid (HF) have been documented in mouse but not human embryos. This study examined the effects of HF on sperm motility and survival after various ...
متن کاملTeratogenic effect of hydrosalpinx fluid in humans?
We read with great interest the manuscript by Chan et al. (2003) examining the teratogenicity of hydrosalpinx ¯uid (HF) using a whole rate embryo culture model. Mechanisms of HF formation and its effects on IVF and embryo transfer outcome have been recently reviewed (Ajonuma et al., 2002). Previous studies were conducted during early embryo development when HF that re¯uxed into the uterine cavi...
متن کاملVero cell co-culture counteracts the detrimental effects of hydrosalpinx fluid on the development of mouse embryos in vitro.
Recent studies have suggested that the hydrosalpinx has a negative effect on pregnancy outcome, with markedly diminished implantation and increased early pregnancy loss. Fluid from the hydrosalpinx may leak into and accumulate in the uterine cavity. It is not clear, however if this creates a hostile local environment in the uterus for embryo implantation or exerts a direct embryotoxic effect. T...
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ژورنال
عنوان ژورنال: Systems Biology in Reproductive Medicine
سال: 2017
ISSN: 1939-6368,1939-6376
DOI: 10.1080/19396368.2017.1319993