Immunosuppressive factor from the spleen in gastric cancer patients
نویسندگان
چکیده
منابع مشابه
The spleen plays an immunosuppressive role in patients with gastric cancer: involvement of CD62L+ cells and TGF-beta.
CD62L is the human homologue of the murine lymphocyte homing receptor, mel-14. We investigated CD62L + cells in the spleen from patients with gastric cancer. Flow cytometric analysis revealed that CD62L + cells were decreased in the peripheral blood, but inversely increased in the spleen in parallel with disease progression in gastric cancer patients. The increased CD62L+ cells resided in the C...
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Lymphocyte subpopulations in peripheral blood and the spleen from gastric cancer patients were identified by either single or two color analysis with fluorescence activated cell sorter-IV (FACS-IV) using monoclonal antibodies. The absolute and percentages of CD3+ (mature T) cells and CD4+ (helper/inducer T) cells in peripheral blood from the advanced cancer patients were significantly lower tha...
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ژورنال
عنوان ژورنال: Cancer
سال: 1985
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19851015)56:8<1963::aid-cncr2820560812>3.0.co;2-t