منابع مشابه
Nerve damage, surgery and rehabilitation in leprosy.
Introduction sy is the only bacterial disease chary the causative organisms infecting the nerves. Clinical or histological tion of peripheral nerve involvement in lesion or elsewhere is an essential criterion for leprosy. The consequences ral nerve involvement result in great and social stigma associated with twithstanding all this, our knowledge of lvement and damage in leprosy is d our abilit...
متن کاملChallenges presented by nerve damage in leprosy.
The basis of nerve damage in leprosy is the unique tendency of Mycobacterium leprae to invade Schwann cells. alphaBeta-Dystroglycan on the basement membrane of Schwann cells binds to laminin alpha2, in turn binding to receptors on the M. leprae surface, comprising a histone-like protein and phenoglycolipid-1. When nerve damage during reversal reactions was found to be associated with an abrupt ...
متن کاملAnti-ceramide antibodies in leprosy: marker for nerve damage?
BACKGROUND Leprosy is a chronic infectious disease primarily affecting the peripheral nervous system and skin. Multibacillary leprosy is associated with nerve damage which could contribute to myelin alteration. As ceramide is a constituent of myelin sheath, the present study aimed to compare anti-ceramide antibody titre in paucibacillary and multibacillary leprosy patients with controls. METH...
متن کاملEmerging Concept on Peripheral Nerve damage in Leprosy
In spite of the many advances in the understanding of leprosy and its management, leprosy evokes fear in the common man and in professionals alike. In a recent survey in western countries, it was surprising to find that, when asked, people preferred to contract AIDS rather than leprosy. There is no doubt that ignorance about leprosy is the major factor in this public reaction. However, it is im...
متن کاملCorticosteroids for treating nerve damage in leprosy. A Cochrane review.
OBJECTIVE Corticosteroids are commonly used for treating nerve damage in leprosy. We assessed the effectiveness of corticosteroids for treating nerve damage due to leprosy. METHODS A systematic search was undertaken to identify randomised controlled trials (RCTs) comparing corticosteroids with placebo or with no treatment. Two authors independently assessed quality and extracted data. Where i...
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ژورنال
عنوان ژورنال: Leprosy Review
سال: 1981
ISSN: 0305-7518
DOI: 10.5935/0305-7518.19810047