Immunopathology of Chronic Rhinosinusitis in Young Children

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منابع مشابه

Immunopathology of chronic rhinosinusitis in young children.

OBJECTIVE Previous investigation demonstrated predominantly lymphocytic inflammation in sinus mucosa of young children with chronic rhinosinusitis (CRS) rather than eosinophilic inflammation typical of adult CRS. Immunohistopathological study was undertaken to define further the cellular response in pediatric CRS. STUDY DESIGN Maxillary mucosal biopsies from children and adults with CRS were ...

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Immunopathology features of chronic rhinosinusitis in high-altitude dwelling Tibetans

Chronic rhinosinusitis (CRS) presents distinct inflammatory and remodeling patterns in different populations and environments. Tibetan ethnic groups live at high altitudes and in cold weather conditions. We sought to examine whether Tibetans exhibit distinct CRS pathology or characteristics. Sinonasal polyps and mucosal tissue were obtained from 14 Tibetan patients with CRS and nasal polyps (CR...

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Chronic rhinosinusitis in children.

Chronic rhinosinusitis (CRS) affects nearly 37 million people in the United States each year and accounts for approximately $6 billion in direct and indirect health care costs. Despite its prevalence and significant impact, little is known about its exact cause and pathophysiology, and significant controversy remains regarding appropriate treatment options. Basic science research, however, has ...

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Chronic Rhinosinusitis in Children

Rhinosinusitis is a very common disease worldwide and specifically in the US population. It is a common disease in children but may be underdiagnosed. Several reasons may account to the disease being missed in children. The symptoms in children are limited and can be very similar to the common cold or allergic symptoms. Cough and nasal discharge may be the only symptoms present in children. A h...

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Evaluation of Children with Chronic Rhinosinusitis after Adenotonsillectomy

Introduction: Chronic rhinosinusitis (CRS), defined as an inflammatory process involving the paranasal sinuses that continues for at least three months, is a major cause of morbidity in the pediatric population and a difficult entity to treat with a poorly defined pathophysiology. The cornerstone of treatment for children with CRS remains aggressive antibiotic therapy, but many patients fail t...

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ژورنال

عنوان ژورنال: Pediatrics

سال: 2009

ISSN: 0031-4005,1098-4275

DOI: 10.1542/peds.2009-1870vv