Immunomodulatory Activity of Recombinant Ricin Toxin Binding Subunit B (RTB)

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Immunomodulatory Activity of Recombinant Ricin Toxin Binding Subunit B (RTB)

Ricin toxin binding subunit B (RTB) is one of the subunits of the ricin protein. RTB has been used as adjuvant, but little is known about its mechanism. In this study, we found that RTB increased not only nitric oxide (NO) release, but also tumor necrosis factor (TNF)-α and interleukin (IL)-6 production in mouse macrophage cell line RAW264.7 cells. They subsequently exhibited enhanced ConA-indu...

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ژورنال

عنوان ژورنال: International Journal of Molecular Sciences

سال: 2013

ISSN: 1422-0067

DOI: 10.3390/ijms140612401