Immunological response in health care workers post COVID-19 vaccination

To curb SARS-CoV-2, various vaccines received Emergency Authorization Use by copious agencies. These are administered to health-care workers, front-line elderly individuals and many others. Health care workers were the first be with vaccines, thus, evaluating antibody response helps portray a picture of burden SARS-CoV-2 infection amid Care Workers. The present study aimed investigate production total antibodies against before after vaccination (2 doses) among Workers along associated factors. was conducted on 60 healthcare as cases who got vaccinated for COVID-19. semi-quantitative detection anti-SARS-CoV-2 IgG Ab in samples detected using Erba Lisa COVID-19 indirect ELISA kit standard protocol described manufacturer. In study, co-morbidities such hypertension presented only 8 (12.3%) individuals, diabetes 4 (6.1%) Coronary Artery Disease 1 (1.5%). After dose administration, 86.67% HCWs found seropositive while 13.33% seronegative, however, second 100% seroprevalence observed HCWs. statistical analysis depicted significant difference (p<0.0001) titres vaccination. mean levels at zero week (4.1), 4th week, (39.09), 8th (79.39) 12th (105). provides important information detectable induced COVISHIELD which independent gender age.