Immunological Outcomes of Allergen-Specific Immunotherapy in Food Allergy
نویسندگان
چکیده
منابع مشابه
Allergen-Specific Immunotherapy in Food Allergy: There Is Hope
While the efficacy of classical subcutaneous allergen-specific immunotherapy (ASIT) has been proven by a multitude of double-blind placebo-controlled trials for various allergens and clinical conditions such as allergic rhinoconjuncitivis, allergic bronchial asthma or insect venom anaphylaxis, patients suffering from food allergy are still left with the simple recommendation of avoidance. This ...
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Although great progress has been made to elucidate the molecular and cellular basis of allergic disorders, it is not completely understood why some individuals develop allergic sensitization to some foods, while the majority of individuals are immunologically tolerant. In addition, it is yet not fully understood which is the molecular basis involved in the immunopathogenesis of the mechanisms e...
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since 20th century, when allergy was defined, an ongoing attempt for discovering the mechanisms underlying it and its treatment began. defining allergens as well as cells such as regulatory t-cells and characterizing the antibodies involved in the pathogenesis (including blocking antibodies) have helped very much towards a better understanding of the immunologic process.however, allergen speci...
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UNLABELLED Immunotherapy selectively modulates the allergen-specific immune response. It involves the gradual administration of increasing amounts of allergen for the purpose of inducing protective immunological changes and it is the only curative approach for specific type I allergy. AIM Description of the allergic inflammation.- Comprehension of the early cellular changes after specific imm...
متن کاملAllergen-Specific Immunotherapy in Food Anaphylaxis
Specific immunotherapy (SIT) protocols for nutritional allergens have only recently been established with a focus on oral allergy syndrome because of pollen cross-reacting antibodies. For these patients, a substantial number of studies have been published suggesting benefits from SIT. The situation in true anaphylaxis to food allergens such as peanut allergy is more complex, and therapeutic str...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2020
ISSN: 1664-3224
DOI: 10.3389/fimmu.2020.568598