Immunologic Effects of Beryllium Exposure

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چکیده

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منابع مشابه

Beryllium exposure and pulmonary function: a cross sectional study of beryllium workers.

A cross sectional study of 297 white male workers employed in a large beryllium plant was conducted to test the hypothesis that long term exposure to beryllium is associated with decrements in pulmonary function. Spirometric measurement of pulmonary function, chest radiographs, and arterial blood gas measurements were collected. After controlling for age, height, and smoking in multivariate reg...

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Characteristics of beryllium exposure to small particles at a beryllium production facility.

Epidemiological studies have reported process-specific elevated prevalence of beryllium sensitization (BeS) and chronic beryllium disease (CBD) among workers. However, exposure-response relationships have been inconsistent, possibly due to incomplete characterization of many biologically relevant aspects of exposure, including particle size. In 1999, two surveys were conducted 3-5 months apart ...

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Beryllium Carcinogenesis I. Inhalation Exposure of Rats to Beryllium Sulfate Aerosol1

One hundred fifty rats (with equal number of controls) were exposed to the inhalation of beryllium sulfate aerosol at a mean atmospheric concentration of 34.25 ¿ig of Be/cu m, and sacrificed in monthly groups during 72 weeks of exposure. Average lung weight towards the end of exposure was 4.25 times normal. Histopathologic examination disclosed 2 gradually developing pathologic processes: (a) ...

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Beryllium carcinogenesis. I. Inhalation exposure of rats to beryllium sulfate aerosol.

One hundred fifty rats (with equal number of controls) were exposed to the inhalation of beryllium sulfate aerosol at a mean atmospheric concentration of 34.25 ¿ig of Be/cu m, and sacrificed in monthly groups during 72 weeks of exposure. Average lung weight towards the end of exposure was 4.25 times normal. Histopathologic examination disclosed 2 gradually developing pathologic processes: (a) ...

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Progression from Beryllium Exposure to Chronic Beryllium Disease: An Analytic Model

BACKGROUND Understanding the progression from beryllium exposure (BeE) to chronic beryllium disease (CBD) is essential for optimizing screening and early intervention to prevent CBD. METHODS We developed an analytic markov model of progression to cbd that assigns annual probabilities for progression through three states: from BeE to beryllium sensitization and then to CBD. We used calculation...

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ژورنال

عنوان ژورنال: Annals of the American Thoracic Society

سال: 2018

ISSN: 2329-6933,2325-6621

DOI: 10.1513/annalsats.201707-573mg