Immunohistochemical features for prognosis of epithelialmesenchymal transformation and stem cell phenotype of small cell lung cancers

Small cell lung cancer (SCLC) is one of the most aggressive tumor human body and has morphological features cancers with epithelial-mesenchymal transformation (EMT). The aim our study to improve for SCLC course prediction based on researching EMT stem cells phenotype at molecular-biological level. prognostic significance pancytokeratin, vimentin, E-cadherin N-cadherin expression, stage expression CD44 overall survival their influence spread were established. It was proved that presence associated extensive forms (p < 0.01), patients depended 0.01) its 0.01).