Immunohistochemical Demonstration of EMA/Glut1-Positive Perineurial Cells and CD34-Positive Fibroblastic Cells in Peripheral Nerve Sheath Tumors
نویسندگان
چکیده
منابع مشابه
Intrathoracic Malignant Peripheral Nerve Sheath Tumor: Histopathological and Immunohistochemical Features
Malignant peripheral nerve sheath tumor (MPNST) is a rare nerve sheath tumor derived from Schwann cells or pleuripotent cells of neural crest. Neurogenic tumors make about 10-20% of all mediastinal tumors. Incidence of MPNST is 0.001% in general population and 0.16% in patients with neurofibromatosis I (NF I). We report a case of 60 year female presenting with progressive cough and breathlessne...
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To determine whether CD34 expression in nerve sheath lesions was found in a unique cell population or in a subset of nerve sheath cells, we performed double immunohistochemical staining using a standard avidinbiotin complex method with 2 separate color developing systems. We studied 40 neurofibromas and 16 neurilemomas. All lesions strongly expressed S-100 in nuclei and cytoplasm. CD34 was dete...
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Cellular expression of the CD34 antigen identifies a morph o l ogi c a lly and immu n o l ogi c a lly heterogeneous cell population that is function-a lly ch a racteri zed by the in vi tro c a p a bi l i ty to gen era te cl onal aggrega tes derived from early and late progenitors and the in vivo capacity to reconstitute the myelo-lymphopoietic system in a supralethally irradiated host. Im mu n ...
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ژورنال
عنوان ژورنال: Modern Pathology
سال: 2003
ISSN: 0893-3952,1530-0285
DOI: 10.1097/01.mp.0000062654.83617.b7