Immunohistochemical Characterization of FacioscapulohumeralMuscular Dystrophy Muscle Biopsies

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Immunohistochemical Characterization of FacioscapulohumeralMuscular Dystrophy Muscle Biopsies

BACKGROUND Posited pathological mechanisms in Facioscapulohumeral Muscular Dystrophy (FSHD) include activation in somatic tissue of normally silenced genes, increased susceptibility to oxidative stress, and induction of apoptosis. OBJECTIVE To determine the histopathological changes in FSHD muscle biopsies and compare to possible pathological mechanisms of disease. METHODS We performed a cr...

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ژورنال

عنوان ژورنال: Journal of Neuromuscular Diseases

سال: 2015

ISSN: 2214-3599,2214-3602

DOI: 10.3233/jnd-150077