منابع مشابه
Immunoglobulin G4-Related Thyroid Diseases.
Immunoglobulin G4-related disease (IgG4-RD) is a new disease category involving many organ systems, including the endocrine system in general and the thyroid in particular. Since an initial association was made between hypothyroidism and autoimmune (IgG4-related) pancreatitis, more forms of IgG4-related thyroid disease (IgG4-RTD) have been recognized. Four subcategories of IgG4-RTD have so far ...
متن کاملImmunoglobulin G4 and related diseases.
i mmunoglobulins, produced by plasma cells, are the effector arm of the humoral immune system [1]. Each immunoglobulin consists of two identical heavy chains (α, β, γ, δ or ε – all encoded by chromosome 14) and two identical light chains (either κ or λ, encoded by chromosome 2 and 22, respectively) [2]. The immunoglobulins have constant (C) regions (similar within the same isotype) and variable...
متن کاملImmunoglobulin G4-related kidney diseases: An updated review
This review will encompass definition, pathogenesis, renal clinical manifestations and treatment of immunoglobulin G4-related diseases (IgG4-RDs). IgG4-RD is a recently recognized clinical entity that often involves multiple organs and is characterized by high levels of serum immunoglobulins G4, dense infiltration of IgG4+ cells and storiform fibrosis. Cellular immunity, particularly T-cell med...
متن کاملImmunoglobulin G4-Related Inflammatory Aortic Aneurysm
1.1 The concept of immunoglobulin G4-related sclerosing disease Immunoglobulin G4 (IgG4) is the rarest subclass of IgG, which is numbered 1 through 4 in the order of their discovery and serum concentration, and normally constitutes only 3 to 6% of the total IgG fraction (Oxelius, 2008). IgG4 antibody has unique structural and functional properties, and the production of IgG4 appears to be drive...
متن کاملImmunoglobulin-G4 related mastitis: A case report☆
INTRODUCTION IgG4-related mastitis (IgG4-RM) is exceedingly rare with only ten cases reported in the literature to date. Organs that are affected with IgG4-related disease (IgG4-RD) all share the same histopathological hallmarks consisting of dense lymphocytic infiltration, storiform fibrosis and obliterative phlebitis. PRESENTATION OF CASE This case report highlights a case of IgG4-RM found ...
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ژورنال
عنوان ژورنال: European Thyroid Journal
سال: 2016
ISSN: 2235-0640,2235-0802
DOI: 10.1159/000452623