Immunofluorescent staining of tubulin in the squid giant axon.
نویسندگان
چکیده
منابع مشابه
Slow transport of unpolymerized tubulin and polymerized neurofilament in the squid giant axon.
A major issue in the slow transport of cytoskeletal proteins is the form in which they are transported. We have investigated the possibility that unpolymerized as well as polymerized cytoskeletal proteins can be actively transported in axons. We report the active transport of highly diffusible tubulin oligomers, as well as transport of the less diffusible neurofilament polymers. After injection...
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Longitudinal alternating current impedance measurements have been made on the squid giant axon over the frequency range from 30 cycles per second to 200 kc. per second. Large sea water electrodes were used and the inter-electrode length was immersed in oil. The impedance at high frequency was approximately as predicted theoretically on the basis of the poorly conducting dielectric characteristi...
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The electrical properties of the giant axon from the common squid Loligo pealei have been reexamined. The primary motivation for this work was the observation that the refractoriness of the axon was significantly greater than the predictions of the standard model of nerve excitability. In particular, the axon fired only once in response to a sustained, suprathreshold stimulus. Similarly, only a...
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We report on a theoretical study showing that the leak conductance density, G{L} , in the squid giant axon appears to be optimal for the action potential firing frequency. More precisely, the standard assumption that the leak current is composed of chloride ions leads to the result that the experimental value for G{L} is very close to the optimal value in the Hodgkin-Huxley model, which minimiz...
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The work of Weiss and his associates,1-3 and more recently of a number of other investigators,4has established the occurrence of a flux of materials from the soma of neurons toward the peripheral regions of the axon. It has been postulated that this mechanism would account for the origin of most of the axonal protein, although the time required to cover the distance which separates some axonal ...
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ژورنال
عنوان ژورنال: Proceedings of the Japan Academy, Series B
سال: 1979
ISSN: 0386-2208,1349-2896
DOI: 10.2183/pjab.55.380