Immunofluorescence studies of florid rheumatic Aschoff lesions
نویسندگان
چکیده
منابع مشابه
Cardiac Lesions Resembling Aschoff Bodies in Rabbits
Cardiac lesions, resembling those of human rheumatic fever, have been observed in rabbits during the course of a seemingly spontaneous epizootic.
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1. In rheumatic myocarditis, foci, termed submiliary nodules of Aschoff, are present which are characteristic of the rheumatic infection. 2. They are most frequently found in the walls of the left ventricle, the auricles usually escaping. 3. The nodules were found in three cases of chorea without joint manifestations, proving the close relation of this condition to rheumatism. 4. They were abse...
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COMPARATIVE STUDIES ON THE HISTOPATHOGENESIS OF EXPERIMENTALLY INDUCED LESIONS OF MYOCARDIAL ASCHOFF BODY TYPE IN RABBITS AND OF MANY MYOCARDIAL ASCHOFF BODIES FROM SEVERAL ACTIVE RHEUMATIC FEVER PATIENTS HAVE REVEALED THE FOLLOWING: Almost invariably these experimental lesions and very frequently the myocardial Aschoff bodies studied in their early stages have been shown to originate in and ev...
متن کاملStudies of Rheumatic
At the present time the available evidence is insufficient to establish definitely the etiology of rheumatic disease although promising work has been done and is in progress. It has long been recognized that there is a tendency for the disease to occur more frequently in some families than in others. In a previous study (1) based upon the records of the families of patients admitted to the Card...
متن کاملJarisch-Herxheimer reaction in complement-depleted rabbits. Histological and immunofluorescence studies of early cutaneous lesions.
The possible role of complement in the pathogenesis of the Jarisch-Herxheimer reaction was assessed in cutaneous syphilitic lesions in two groups of rabbits treated with penicillin; in one group complement was depleted before penicillin therapy. Serial biopsy specimens were similar histologically in both groups. The activation of the complement pathways did not seem to play a role in the pathog...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1986
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.1780290208